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These phenotypic hallmarks indicate a disruption in the finely tuned epigenetic regulation of genes required for proper growth and neurodevelopment

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Although the enrichment of L-cells by pharmacological agents can be a novel approach for improving insulin secretion, glucose tolerance and the treatment of T2DM, more research for the specific differentiation of L-cells and the translation of in vitro and animal data to humans, are needed for the success of this approach

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Dietary sources are essential, primarily found in animal products like meat, fish, eggs, and dairy

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