Natural GLP-1 is an incretin hormone (a gut hormone) that is secreted after ingesting meals that stimulates the release of insulin while also slowing digestion and suppressing appetite
As of May 2026, retatrutide doesnt have a UK marketing authorisation, which means no UK pharmacy or licensed clinic can legally dispense it
Anderson SR, Ayoub M, Coats S, McHenry S, Tan T, Deepak P
By implementing a comprehensive bone protection protocol that includes targeted supplementation, appropriate exercise, and regular monitoring, you can help ensure that your weight loss journey supports rather than compromises your long-term health and mobility
Next Steps If your IGF-1 is outside the optimal range, the first step is a comprehensive evaluation with a functional medicine provider who understands both lifestyle interventions and advanced therapies like peptides
Ages 60 and older, a history of kidney disease or kidney failure, and individuals using medications such as blood thinners, immunosuppressants or corticosteroids, may increase the risk of developing side effects including joint pain