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McPherson SJ, Ellem SJ, Simpson ER, Patchev V, Fritzemeier KH, Risbridger GP

Here, we investigated the effect of a fasted versus fed state (food-effect) on the pharmacokinetics (PK), safety, and tolerability of single and multiple oral doses of orforglipron in healthy adults in two phase 1 studies (A and B)

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It was built from the ground up to integrate obesity medicine , primary care, and metabolic health serving as the clinical bridge between traditional health systems and the fast-moving GLP-1 economy

Our study highlights the importance of validating genomic predictions using rigorous behavioral data before translating them into personalized health recommendations

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