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The capsule polysaccharide from serogroups A, B, C, W, and Y meningococci inhibits C1q interaction with bound anti-fHbp and anti-porin A antibodies, and, consequently, the deposition of C4b and classical complement pathway (Jarvis and Vedros, 1987), as well as LOS sialylation (Vogel et al., 1997), limits C3 deposition, inhibiting the alternative pathway