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Furthermore, both SM and exenatide selectively activated p38 MAPK phosphorylation in the spinal cord, providing additional evidence that SM exerts its anti-allodynic effects by targeting spinal GLP-1R and promoting microglial -endorphin synthesis via the p38 MAPK signaling cascade [72]

Popovitz, M

1 Flow chart of the review process

It is imperative to note that each patient is unique and may not even face most of these side-effects given that they follow their post-op plan to the last detail

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