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Excessive muscle loss can: A 2023 study published in Obesity found that up to 39% of the weight lost on semaglutide came from lean body massunderscoring the need for protective strategies

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Skin elasticity using a cutometer was measured at baseline, at 4 weeks, and then 4 weeks after discontinuation of the treatment, which showed significant improvement in skin elasticity, even in sun-exposed skin areas, during these time points compared with baseline values [39]

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Notably, among individuals with MASLD, the risk of incident T2DM increases progressively with the severity of liver fibrosis (Mantovani et al., 2021[46])

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