In brief, metabolites were identified based on the Progenesis QI online METLIN database, public databases, and Biomarker Technologys self-built database
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Gonadorelin is a synthetic analog of natural GnRH used diagnostically and therapeutically to assess pituitary function and to induce ovulation
However, a significant proportion of patients are still refractory to pharmacological treatments, so the development of new drugs targeting the underlying mechanisms of UC is necessary to achieve optimal disease control
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Its clinical significance column refers to expanded indications and dosing regimens informed by biomarker data