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Med J Cairo Univ

Betting the same drugs that curb cravings for food will also dampen the rewarding effects of alcohol, cocaine, and opioids, Roberts and 17 other women each grappling with different addictions are receiving free weekly injections of GLP-1 drugs under a pilot program by Open Doors, a Rhode Island nonprofit that helps formerly incarcerated and homeless women reintegrate into society

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Sleep deprivation, chronic stress, and nutrient deficiencies impair leptin signaling and can neutralize appetite-suppression benefits

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While lifestyle modification remains first-line, pharmacological interventions have shown mixed results