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NEW FORMULATION Wegovy is now available as a once-daily oral pill FDA-approved oral GLP-1 Easy, once-daily pill ~14% weight loss at 1 year (similar to injectable) No injections or refrigeration needed Prescription & ongoing care through Healthspan 1 Based on the 64-week OASIS 4 Phase 3 clinical trial of 307 adults with obesity or overweight

Amagase H, Sun B, Borek C

However, the mechanisms by which SGLT2 inhibitors exert these benefits beyond glucose-lowering are not fully understood

for example, NTS PrRP neurons are leptin sensitive in rats but not in mice (61)

Understanding drug interactions is crucial for those taking medications like Ozempic