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The gap between the marketed mechanism (localized IGF-1 receptor activation driving hyperplasia) and lived experience (systemic effects including lethargy, joint pain, and unpredictable blood glucose swings) is what makes community discussion essential

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Testa U, Grignani F, Samoggia P, Zanetti C, Riccioni R, Lo Coco F et al

The results illustrated that the mRNA expression of Nrf2 was notably increased in the CP group (P = 0.0104) and 20 mg/kg glycitin treatment group (P = 0.0302, Figure 6A) in the hippocampus compared with the CN group [F (5, 30) = 7.936, P = 0.0058]

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