Phase 3 protocols often begin at 2mg
Cost and side effects are the most common reasons people discontinue treatment
Even in that population, retatrutide demonstrated nearly 21 percent average weight loss at the highest dose, which is remarkable. Retatrutide Also Delivered Significant Results for People With Severe Obesity and Heart Disease The other trial, TRIUMPH-3, included nearly 2,000 adults with severe obesity (defined as a BMI of 40 or higher) and cardiovascular disease
[] Additionally, GLP-2 and GIP both minimize bone resorption in humans, [] but the molecular mechanism involved is poorly understood
Although these data demonstrate the potential for targeted remodeling of neurons expressing the GLP-1 receptor to treat obesity, these preclinical findings must be evaluated in humans
For someone looking to improve their overall protein intake, adding gelatin or collagen to smoothies, coffee, or other foods is fine