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High remission rate, short remission duration in patients with refractory anemia with excess blasts (RAEB) in transformation (RAEB-t) given acute myelogenous leukemia (AML)-type chemotherapy in combination with granulocyte-CSF (G-CSF)

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extended release version approved in 2017 Side Effect Update Date: May 28, 2025 Medication Description: Treats type 2 diabetes Updated Side Effects/Safety Information: A new warning about the risk of serious kidney injury caused by dehydration due to gastrointestinal adverse effects like diarrhea and vomiting

YTHDF2 promotes the degradation of ZHX2 mRNA To investigate the underlying mechanism behind the decrease in hepatic ZHX2 expression in diabetic mice, we utilized SRAMP (sequence-based RNA adenosine methylation site predictor) to analyze the sequence of ZHX2 mRNA

GIP receptor signaling increases cAMP levels in the brain, which activates PKA and EPAC [102]