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Injection Site Reactions: Normal vs Concerning Mild redness, warmth, and a small raised area at the injection site lasting 2448 hours is a normal inflammatory response to subcutaneous fluid deposition

Unreconstituted PT-141 vials should be stored refrigerated at 28C in lyophilized (powder) form, protected from light and moisture

Insufficient buffering: Reconstituting GHK-Cu without adequate bacteriostatic saline, or using a solvent that does not adequately buffer the solutions pH, leaves the compound in a form that is more likely to cause tissue irritation on delivery

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Meanwhile, the antibacterial spectrum is enlarged, indicating that synergetic effective composite hydrogels have great potential clinically

PMID: 35015037 Lincoff AM, Brown-Frandsen K, Colhoun HM, et al