Our data suggest exendin-P5 may induce a looser coupling between the ligand TMD and G s binding sites, potentially linked to the more short-lived interactions with TMD residues, resulting in higher efficacy due to faster G s conformational transitions associated with nucleotide exchange and faster G s dissociation
Xiaoran A, Jiapei Y, Xiaolin C, Jiaxuan Z, Chenwei J, Minglu T, Yabing D, Longfei L, Hui L, Feihu W
Many women choose to resume therapy to prevent postpartum weight regain
Christou, A., Manganaris, G
However, results across studies vary, and larger trials are necessary to confirm these preliminary findings
Fast acting but short-lived