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(PubMed) Perrig WJ, Perrig P, Stahelin HB
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Interestingly, despite the presence of superoxide dismutase (SOD) ( k = 2.4 10 9 M 1 s 1 ) 36 , the resulting concentration of H 2 O 2 is significantly smaller than the concentration of superoxide, indicating that the model is able to respond well to a transient increase in ROS, maintaining low H 2 O 2 concentrations
Parkinsons Disease
Clinical trials assessing these effects in humans receiving NAD+ injection have not yet been published
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Moreover, H 2 O 2 /O/OH modulate metabolic pathways, such as the tricarboxylic acid cycle and mitochondrial function, thereby indirectly influencing the availability of essential metabolites required for epigenetic enzyme modifications [164]
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