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Because the Secretary updates the ASC payment amounts annually, we adopted a policy, which we codified at 416.171(a)(2)(ii)), to update the ASC conversion factor using the CPI-U for CY 2010 and subsequent calendar years

a and b : Principal component analysis of liver ( a ) and skeletal muscle gene expression ( b )

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and if the drug was given once a day, the dose would be 700 mg