Once breakdown starts, a protein called intrinsic factor, released by parietal cells in the stomach, binds to vitamin B12 in the duodenum (small intestine) and forms a B12-intrinsic factor complex that allows B12 to be absorbed in the terminal portion of the small intestine
doi: 10.1152/ajpendo.00402.2009
Riboflavin has also been linked with the potential prevention of early aging, the ability to reduce your risk of heart disease, headache prevention, and the metabolism of fats and carbohydrates
The agency cited safety risks including potential carcinogenicity, immunogenicity, and concerns about impurities and noted that most of these substances had never undergone rigorous human clinical trials
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