are glp 1 safe in pregnancy Use of GLP-1 drugs early should not cause alarm, analysis suggests Preconception GLP-1 receptor agonist use

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Excess adipose tissue can also increase the conversion of testosterone into estradiol, shifting the hormonal environment away from sperm production

10.1002/smll.202203725 57 RaoJ.DjeffalY.ChalJ.MarchianF.WangC

10.1038/s41589-018-0031-6 57 GaschlerM

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The mechanism is well-characterized in rodent models but not confirmed at the tissue level in human injectable studies for musculoskeletal indications