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Keap1 is a Cys-rich protein, and its persulfidation has been well documented

Damaged mitochondria release cardiolipin and other bioactive molecules that activate Nucleotide oligomerization domain (NOD)-like receptors, contributing to elevated levels of pro-inflammatory cytokines and chemokines and result in sustained renal inflammation and injury (Szeto et al., 2017)

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Biochemistry (2001) 40:1413442.10.1021/bi011459o 39 XieYKoleSPrechtPPazinMJBernierM

13 GLP-1 RAs are very effective in lowering blood sugar levels