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In humans, cyanocobalamin must undergo intracellular enzymatic conversion to the active coenzyme formsmethylcobalamin and adenosylcobalaminwhich, depending on the pH environment, can interconvert with hydroxocobalamin (Gherasim et al., 2013), the most common B12 form in both food and human plasma (Obeid et al., 2015)

These actions enhance nutrient and oxygen delivery to aging tissues, encouraging collagen renewal and improved elasticity

in coeliac or Crohns disease), this can lead to B12 deficiency

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