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Ultimately, what these crystal structures of monofunctional catalases reveal is that they consist of four tightly integrated protein subunits, each of around 55 to 69 kDa for clades 1 and 3 catalases (i.e., small-subunit catalases or SSCs such as BLC), and around 75 to 86 kDa from clade 2 (i.e., large-subunit catalases or LSCs)

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However, the prolonged accumulation of senescent cells can paradoxically induce cancer development and various age-related diseases by inducing an inflammatory environment via the SASP 47-49

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