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This pathway has been targeted pharmacologically through the development of DPP-4 inhibitors, and these are now a successful class of anti-hyperglycaemic agents used to treat type 2 diabetes (T2DM)

These are generally mild and tend to resolve on their own

Common gastrointestinal side effects These are the most frequently reported: Practical strategies that may help some people include smaller meals, eating more slowly, avoiding very high-fat meals during dose increases, and staying hydrated

Neurobiology of Aging 27, 57688

19 Briefly, cycloheximide (10 g/ml) was added into the culture medium and incubated for 10 min before cells were harvested

It could also be due to: physical injury from an accident having surgery exposure to toxins blood loss mental and emotional stress Any sudden change that your body registers as stress or a shock to the system can cause telogen effluvium , including rapid weight loss