A Quick Reference for Non-Specialist Clinicians LIKELY APPROPRIATE BMI 35, no eating disorder history Type 2 diabetes + overweight Cardiovascular risk reduction Metabolic syndrome REQUIRES EATING DISORDER SPECIALIST CONSULT FIRST Binge eating disorder Any prior mental health diagnosis History of disordered eating Adolescents / young adults DO NOT PRESCRIBE / HIGH RISK Active anorexia nervosa Active restrictive eating disorder History of MTC or MEN2 Active pancreatitis A Note on Autonomy, Judgment, and What We Owe Our Patients The following reflects my personal opinion and clinical perspective
However, ePA vendors typically have robust security
If you change your mind, you can later opt out of this long-term follow-up if you wish
The active, intact molecule is essentially destroyed before it can ever reach the bloodstream or enter the cells where it is desperately needed
Earlier therapies targeted the receptors for CRH or corticosterone, but they didnt actually lower stress hormone levels themselves
The same pacing applies to changes in A1c