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Many patients on GLP-1 medications lose an average of 10% to 15% of their body weight over 12-18 months, depending on their body mass index, dose, and adherence to a treatment plan

This may cause severe nausea, persistent vomiting, or a dangerous drop in blood sugar

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In patients receiving cagrilintide 2.4 mg plus semaglutide, there was a mean body weight change from baseline of -17.1% compared to -9.8% with semaglutide alone

**Plasmapheresis is a therapeutic intervention that involves extracorporeal removal, return, or exchange of blood plasma or components