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Overall Homeostasis: GPxs maintain cellular redox, preventing oxidative damage in immune processes

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The function of activated microglia/macrophages may depend on the time and microenvironment of the brain pathology

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Mitochondrial function, necessary for both the TCA cycle and OXPHOS, is also supported by mTORC1 signaling ( Although glycolytic upregulation can be used as an indicator of permissivity to infection, Guo et al

PLoS ONE 6 , e22640 (2011)