Oral thrush, skin infections, yeast infections, and even systemic (invasive) candidiasis can occur in men, women, and children
Parenteral administration is typically used to treat vitamin B12 deficiency caused by pernicious anemia as well as other conditions (e.g., tropical sprue, pancreatic insufficiency) that result in vitamin B12 malabsorption and severe vitamin B12 deficiency
dietary supplement, health food, cosmetic, and pharmaceutical industries
10.1021/ja104683w 195 WangD.LinZ.WangT.YaoZ.QinM.ZhengS.et al (2016)
observed patients after two years of bariatric surgery, who were systematically taking multivitamins containing 2.4 g of vitamin B 12 , that 80% of their patients had a deficit and had to be supplemented [54]
If you're plant-based, you're likely low no matter how clean your diet is, so supplementation isn't optional