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Quoting Watterson, it is doubtful that nature evolved catalytic machines which are on the verge of breakdown each time they begin to function [Web reference 6]

Occasional small leakage isnt concerning, but a pattern suggests a technique issue worth discussing

History and origin of the ketogenic diet

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357 This metabolic reprogramming is often accompanied by enhanced antioxidant capacity, allowing CSCs to neutralize therapy-induced oxidative stress