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Thyroid hormone production, apoptosis, and immunological dysfunction have all been associated with dysregulation of miRNAs

Here, solubility refers to the actual solubility of the two niclosamide species, i.e., the protonated acid (Nic OH ) and unprotonated salt (Nic -ve ) which are measured to be 1.77uM (at pH 3.66) and 641uM at pH 9.5

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However, tesofensine is a novel compound with potential in human studies and may be a promising alternative for these patients [38]