Base excision repair is the primary pathway of DNA damage repair in neurons
30 PKA then promotes the synthesis of insulin peptide precursor in beta-pancreatic cells and inhibits the release of glucagon by alpha pancreatic cells
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When to seek urgent medical attention : Severe, persistent abdominal pain (particularly if radiating to the back) Bloody diarrhoea or significant increase in stool frequency Signs of dehydration (dizziness, reduced urine output, dry mouth) Persistent vomiting preventing oral intake Fever accompanying gastrointestinal symptoms Patients should contact their GP or IBD team promptly if they experience worsening symptoms that could indicate either a Crohn's flare or serious medication side effects
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