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In experimental models it modulates angiogenesis (upregulating VEGF/VEGFR2 and the nitric oxide pathway), reduces pro-inflammatory cytokine signaling, supports fibroblast migration and collagen synthesis for connective-tissue repair, and influences gut-barrier integrity and neural pathways mechanisms that span musculoskeletal, gastrointestinal, and neurological tissue in preclinical research

After reconstitution, refrigeration is recommended

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Macrophages can secrete various cytokines, such as TNF-, IL-1, IL-6, IL-7, IL-15, IL-18, IL-23