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We also review therapeutic approaches for enhancing GSH status

For example, CD34CD38 cells in AML, 25,26 CD133 cells in GBM, 28,29 and CD44CD24 cells in breast cancer 27 have been shown to generate tumors in such models

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Li Q, Wu S, Li SY, Lopez FL, Du M, Kajstura J, Anversa P, Ren J: Cardiac-specific overexpression of insulin-like growth factor 1 attenuates aging-associated cardiac diastolic contractile dysfunction and protein damage

Its diabetes drug Mounjaro has seen robust growth in the ~18 months that it has been on the market