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However, owing to the narrow therapeutic window, NAC needs to be used within 8 h after APAP poisoning to achieve good therapeutic efficacy

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D., Hayes-Larson, E., Morris, E

Encapsulated within cRGD-modified cationic liposomes to ensure CSC targeting and lysosomal escape, the prodrug is activated specifically in the reactive oxygen species (ROS)-rich CSC environment upon thioketal cleavage