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ESCRT-1 and ESCRT-2 control the initiation of the budding process and facilitate the enzymatic de-ubiquitination of cargo proteins before the formation of intraluminal vesicles (ILVs)

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It is a well-characterized molecule with a substantial research base

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Last reviewed: May 31, 2026 Last updated: May 31, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations