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It acts as a stable pentadecapeptide derived from gastric juice that promotes angiogenesis, upregulates growth factor receptors (EGF, VEGF), and modulates the nitric oxide system to accelerate tissue healing

However, experts in the area generally concur that a combination of data from multiple endpoints is needed to discriminate sensitizing and/or irritant substances in vitro

This observation hints that higher MOTS-c might correlate with better endothelial function, whereas a deficiency in MOTS-c could be linked to vascular problems

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