Functional enrichment indicated strong activation of iron transport and lipid peroxidation pathways, but weak engagement of glutathione metabolism, suggesting selective vulnerability to iron-driven oxidative stress
In Alzheimers disease, NLRP3 inflammasome has emerged as a pathological component participating in the impaired removal of amyloid- by microglia (Lonnemann et al., 2020)
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Reactive oxygen species in the activation of MAP kinases
Patano N, Mancini L, Settanni MP, Strippoli M, Brunetti G, Greco G, Tamma R, Vergari R, Sardelli F, Koverech A, Colucci S, Zallone A, Grano M: L: -carnitine fumarate and isovaleryl-L: -carnitine fumarate accelerate the recovery of bone volume/total volume ratio after experimetally induced osteoporosis in pregnant mice
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