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Central and peripheral neuroendocrine peptides and signalling in appetite regulation: considerations for obesity pharmacotherapy

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Many patients do well long-term at 5 to 10 mg tirzepatide or 1.0 to 1.7 mg semaglutide

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Others find oral medications less effective for appetite control and prefer to stay on injections

While a person eats, hormonal messages traveling via the vagus nerve tell their pancreas to produce insulin, which converts glucose to energy and brings blood glucose levels back down