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[DOI] [PMC free article] [PubMed] [Google Scholar] 67.Ozaydin M., Peker O., Erdogan D., Kapan S., Turker Y., Varol E., Ozguner F., Dogan A., Ibrisim E

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IGF-1R is a receptor tyrosine kinase expressed broadly across muscle, fat, liver, and other tissues

However, in conditions such as AD or PD, where activation is prolonged or chronic, astrocytes may undergo irreversible changes, contributing to neuroinflammation and scarring through the non-cell-autonomous pathways 20