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It may be related to the increase of oxidative damage, so the amount of GSH is a vital factor to measure the body's antioxidant ability

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We also discuss how modulation of the mitochondrial-inflammation axis informs conventional and emerging antidepressant strategies, aiming to advance mechanistic understanding and guide future clinical interventions

evaluated AOD9604 in overweight and obese subjects, comparing various doses administered subcutaneously over 12 weeks