It's not a spot-reduction treatment, and it shouldn't be confused with fat-dissolving injections, which are an entirely different product category with a different risk profile (more on that below)
Lieber RL, Jacks TM, Mohler RL, Schleim K, Haven M, Cuizon D, Gershuni DH, Lopez MA, Hora D Jr, Nargund R, Feeney W, Hickey GJ (1997) Growth hormone secretagogue increases muscle strength during remobilization after canine hindlimb immobilization
These medications potently and selectively inhibit the enzymatic activity of DPP-4, enhancing the effectiveness of GLP-1 and glucose-dependent insulinotropic polypeptide (GIP), which are the primary incretins (endogenous glucoregulatory peptides, [39,40,41])
, Jannat, B
Trends Pharmacol Sci (2012) 33(12):65668.10.1016/j.tips.2012.09.007 65 TewKDTownsendDM
Retatrutide produced 28.7% weight loss in Phase 3 trials