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[1] Patients should be cautioned that the efficacy and safety of MB for these wellness or cognitive applications are not yet established, and such therapy must be closely supervised by a qualified healthcare provider

Reduced Quantal Size : Under repeated amphetamine exposure, the combination of vesicular NE displacement (via proton gradient collapse) and VMAT2 blockade prevents newly recycled or recruited vesicles from being effectively refilled with NE (Sulzer et al, 1995

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This context helps frame glycemic variability beyond food and medications

Additionally, future studies should investigate the long-term effects of microbiome-based interventions and explore the potential of personalized medicine approaches tailored to individual patients gut microbial profiles (Cunningham et al., 2021)