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Despite the significant burden of disease, effective pharmacological options remain limited, leaving lifestyle interventions based on dietary modification and physical activity as the mainstay of clinical management [6]

Starting weight, week one: 212 lb

As the research and development of retatrutide continue, the medical community remains cautiously optimistic about the future of this drug

Long-term cardiovascular outcomes data for retatrutide are not yet available

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The authors also note that the patient did not initially disclose his alcohol use because of guilt and stigma, highlighting the need for stronger AUD screening and diagnostic efforts within family medicine clinics