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Many of these medications were originally developed and approved for the treatment of type 2 diabetes

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The study authors reported weight regain percentages ranging from 1.9% to 14% depending on the agent used.49 These findings, in addition to the STEP 4 trial previously discussed, highlight the potential for significant weight regain once treatment is discontinued and emphasize the importance of discussing long-term treatment planning with patients

10.2165/00007256-199723020-00004 42 FryburgD