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Key Points Injectable semaglutide (Ozempic, Wegovy) requires refrigeration before first use Ozempic can be stored at room temperature after opening for up to 56 days Oral semaglutide (Rybelsus) does not need refrigeration and should be stored at room temperature between 68F and 77F in a dry place Improper storage reduces medication effectiveness by breaking down the molecular structure, leading to poor blood sugar control and diminished weight loss benefits Your semaglutide may sit in your fridge, but you're heading out for a weekend trip

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10.1042/bj20060792 Biochem

These side effects are usually mild and decrease over time

Another area of interest is gastrointestinal support

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