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Metabolomic profiling of anionic metabolites by capillary electrophoresis mass spectrometry

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Concentrations above 3 mg/mL exceed solubility limits and cause peptide precipitation, while concentrations below 0.5 mg/mL require larger administration volumes that exceed the nasal cavity's absorption capacity (approximately 150 L per nostril)

This absence of foundational pharmacokinetic information constitutes a major knowledge gap with direct implications for clinical application, dosing strategies, and safety monitoring

Researchers have investigated BPC-157s potential role in supporting the digestive system and maintaining healthy tissue within the gastrointestinal tract