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The locus for apolipoprotein E (apoE) is linked to the complement component C3 (C3) locus on chromosome 19 in man
MYQORZO (aficamten) , a cardiac myosin inhibitor for the treatment of adults with symptomatic obstructive hypertrophic cardiomyopathy (oHCM), inhibits force in cardiac muscle by altering myosin's biochemical activity without changing thick filament structure
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In addition, Ang-1 mimetic and the inhibition of circulating Ang-2 could reduce vascular permeability [78]
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