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According to clinical observations reported by Integrative Medicine of Los Angeles, an intramuscular B12 injection is absorbed more slowly over a longer time frame compared to an IV infusion, which delivers the nutrient immediately into the vasculature

The ability to shuttle between the +1, +2, and +3 oxidation states is responsible for the versatile chemistry of vitamin B 12 , allowing it to serve as a donor of deoxyadenosyl radical (radical alkyl source) and as a methyl cation equivalent (electrophilic alkyl source)

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A deficiency can erode this coating and cause neuropathy (tingling, numbness, or pain in the hands and feet)

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Absorption: Conditions like celiac disease, IBS, or pernicious anemia can affect how your body takes in B12