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Metabolic reprogramming of glycolysis and glutamine metabolism are key events in myofibroblast transition in systemic sclerosis pathogenesis

Acute exercise temporarily increases DPP-4 activity (likely evolutionary adaptation to manage incretin hormones during physical stress), but chronic regular exercise appears to reduce baseline DPP-4 expression

Because that's one of the things that does happen

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Furthermore, it mixes well with water with an even consistency, which is not too bulky, like some psyllium powders can be