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Why do B12 shots hurt so much when dissolved in water

MOTS-c (short for mitochondrial open-reading-frame of the 12S rRNA type-c) is often dubbed a mitokine a peptide hormone produced by mitochondria that influences metabolism throughout the body

If you've been feeling sluggish or low-energy lately, getting B12 injections might help you get back on track (especially if you have a B12 deficiency)

This paradoxical reaction is not fully understood but is thought to be related to individual metabolic responses

as a key regulator of mitochondrial biogenesis, PGC1 enhances mitochondrial function in myoblasts, supplies sufficient energy for differentiation, and regulates the transcription of myogenic genes to accelerate myotube maturation

Its an excellent option for those combining weight loss with physical activity