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Collectively, these mechanistic insights indicate that incretin mimetics modulate central neuroimmune and bioenergetic pathways directly within neurons and microglia, providing a biological basis for their diseasemodifying potential in neurodegenerative disorders

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The GLP1R agonist liraglutide reduces hyperglucagonemia induced by the SGLT2 inhibitor dapagliflozin via somatostatin release

Curcumin Curcumin, chemically identified as 1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione, is the principal bioactive component derived from the rhizome of Curcuma longa L