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Statins deplete GPX4 expression and mevalonate rescues statin-induced cell death The remarkable overlap between the transcriptional changes induced by RSL3 and simvastatin in both YR1.7 and MC38 led us to question whether statins might also act on GPX4 to promote ferroptosis

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doi: 10.1016/S2213-8587(23)00356-X 13 JastreboffAMKaplanLMFrasJPWuQDuYGurbuzSet al

Taking excessive amounts of these substances can be harmful

This abrupt awakening can occur even after severe poisoning and can make airway management more difficult